Stress, cortisol, and immune function
Wounds of dental students heal more slowly during exam periods than during vacation. Which mechanism best explains this?
Answer B: explanation for every choice
A
Stress shifts autonomic balance toward sympathetic activity, not parasympathetic.
B
Correct. Sustained stress activates the HPA axis, and cortisol suppresses inflammation and immune activity needed for healing.
C
Stress increases ACTH release.
D
Insulin is not the main link between stress and slower healing. Cortisol actually opposes insulin's effects.
TakeawayChronic stress → cortisol → immune suppression.
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Reviewed 2026-11-05 by a medical student. Spot an error? Report it with question ID ps161.