Wobble hypothesis and codon degeneracy
The wobble hypothesis explains why:
Answer C: explanation for every choice
A
Silent mutations are most common at the third position, not the first.
B
Stop codons are recognized by release factors, not explained by wobble.
C
Correct. Base pairing at the codon's third position is flexible, so one anticodon can pair with several codons.
D
AUG coding for methionine is a feature of the genetic code, not of wobble pairing.
TakeawayWobble at the third codon position helps explain why the code is degenerate.
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Reviewed 2026-11-05 by a medical student. Spot an error? Report it with question ID bb43.