Histone acetylation and transcription
Histone acetylation generally:
Answer D: explanation for every choice
A
Condensation and silencing are associated with histone deacetylation.
B
Cytosine methylation is DNA methylation, a separate mechanism.
C
Acetylation is an epigenetic change. It does not alter the DNA sequence.
D
Correct. Acetylation neutralizes the positive charge on lysines, weakening histone–DNA binding and opening chromatin.
TakeawayAcetylation opens chromatin. Deacetylation closes it.
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Reviewed 2026-11-05 by a medical student. Spot an error? Report it with question ID bb46.