Dopamine hypothesis of schizophrenia
Which observation supports the dopamine hypothesis of schizophrenia?
Answer A: explanation for every choice
A
Correct. Antipsychotics block D2 receptors, and their potency tracks their D2 binding.
B
SSRIs treat depression and anxiety, not schizophrenia.
C
This is reversed. Parkinson's medications such as L-dopa raise dopamine, and that can cause psychosis.
D
The hypothesis proposes excess mesolimbic dopamine, not a deficit, behind positive symptoms.
TakeawayExcess mesolimbic dopamine → positive symptoms. Antipsychotics block D2 receptors.
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Reviewed 2026-11-05 by a medical student. Spot an error? Report it with question ID ps61.