Glucokinase vs. hexokinase
How does liver glucokinase differ from hexokinase in other tissues?
Answer D: explanation for every choice
A
This describes hexokinase, which works efficiently even at low glucose levels.
B
Both enzymes phosphorylate glucose at carbon 6.
C
Glucokinase is most active when blood glucose is high.
D
Correct. A high Km lets the liver take up glucose mainly when levels are high, as after a meal, and lack of product inhibition lets it keep storing.
TakeawayHexokinase: low Km, product-inhibited. Glucokinase: high Km, works after meals.
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Reviewed 2026-11-05 by a medical student. Spot an error? Report it with question ID bb114.