Fatty acid synthesis vs. β-oxidation
Which statement about fatty acid synthesis is correct?
Answer B: explanation for every choice
A
β-oxidation, not synthesis, occurs in the mitochondrial matrix.
B
Correct. Synthesis occurs in the cytosol, uses NADPH as the reductant, and is limited by acetyl-CoA carboxylase.
C
β-oxidation produces NADH and FADH2. Synthesis consumes NADPH.
D
CPT-1 is the rate-limiting step of β-oxidation.
TakeawaySynthesis: cytosol, NADPH, acetyl-CoA carboxylase. Oxidation: mitochondria, NAD⁺ and FAD, CPT-1.
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Reviewed 2026-11-05 by a medical student. Spot an error? Report it with question ID bb67.