Regulation of hormone-sensitive lipase
Which pair of hormones activates hormone-sensitive lipase in adipose tissue?
Answer C: explanation for every choice
A
Insulin inhibits hormone-sensitive lipase, promoting fat storage.
B
Insulin inhibits the lipase. Cortisol has slower, supportive effects.
C
Correct. Both raise cAMP, and protein kinase A phosphorylates and activates the lipase, releasing fatty acids.
D
Insulin opposes epinephrine's effect on the lipase.
TakeawayFasting and stress hormones release fat. Insulin stores it.
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Reviewed 2026-11-05 by a medical student. Spot an error? Report it with question ID bb125.