Hard mode

107 questions that take two steps, a calculation, or rejecting an answer that's true somewhere else.

Start a timed hard block

Bio/Biochem 39

  1. Uncouplers vs. electron transport chain inhibitorsMetabolism and bioenergetics · set 3 · hard
  2. A lac operator mutation in a partial diploidGenes and gene expression · set 6 · hard
  3. Competitive inhibition: calculating the new velocityProteins and enzymes · set 3 · hard
  4. Calculating the turnover numberProteins and enzymes · set 3 · hard
  5. Why sickle hemoglobin polymerizes when deoxygenatedProteins and enzymes · set 5 · hard
  6. Glucagon, PFK-2, and fructose-2,6-bisphosphateMetabolism and bioenergetics · set 8 · hard
  7. Acetyl-CoA directs pyruvate's fateMetabolism and bioenergetics · set 8 · hard
  8. Treating pyruvate dehydrogenase deficiencyMetabolism and bioenergetics · set 5 · hard
  9. Anaplerotic reactionsMetabolism and bioenergetics · set 5 · hard
  10. Rotenone and succinate oxidationMetabolism and bioenergetics · set 3 · hard
  11. ATP yield from palmitateMetabolism and bioenergetics · set 7 · hard
  12. The energy cost of gluconeogenesisMetabolism and bioenergetics · set 5 · hard
  13. Aspirin and cyclooxygenaseMetabolism and bioenergetics · set 7 · hard
  14. Recessive risk: an unaffected sibling of an affected childGenetics and evolution · set 3 · hard
  15. X-linked recessive: son of an obligate carrierGenetics and evolution · set 2 · hard
  16. Gene order from recombination frequenciesGenetics and evolution · set 3 · hard
  17. Hardy–Weinberg for an X-linked traitGenetics and evolution · set 4 · hard
  18. Genomic imprintingGenetics and evolution · set 2 · hard
  19. PCR amplification after 10 cyclesGenes and gene expression · set 2 · hard
  20. How enhancers workGenes and gene expression · set 6 · hard
  21. Hyperkalemia and the resting membrane potentialNervous and endocrine systems · set 3 · hard
  22. Tetrodotoxin and action potentialsNervous and endocrine systems · set 3 · hard
  23. The absolute refractory periodNervous and endocrine systems · set 3 · hard
  24. Smooth muscle contractionOrgan systems · set 5 · hard
  25. The cardiac action potential plateauOrgan systems · set 2 · hard
  26. Renal clearance greater than GFROrgan systems · set 6 · hard
  27. Interpreting an arterial blood gasOrgan systems · set 1 · hard
  28. Anemia: PaO₂, saturation, and oxygen contentOrgan systems · set 7 · hard
  29. Hyperpigmentation in Addison's diseaseNervous and endocrine systems · set 2 · hard
  30. Laboratory pattern in early type 2 diabetesNervous and endocrine systems · set 2 · hard
  31. Rh incompatibility and the first pregnancyOrgan systems · set 4 · hard
  32. Why conjugate vaccines work in infantsOrgan systems · set 4 · hard
  33. Analogous structures and convergent evolutionGenetics and evolution · set 1 · hard
  34. Kin selectionGenetics and evolution · set 1 · hard
  35. Energy cost of adding one amino acidGenes and gene expression · set 6 · hard
  36. Digoxin and cardiac contractilityOrgan systems · set 2 · hard
  37. Mixed inhibition on a Lineweaver–Burk plotProteins and enzymes · set 2 · hard
  38. Malonyl-CoA inhibits carnitine acyltransferase IMetabolism and bioenergetics · set 7 · hard
  39. Urea cycle: carbamoyl phosphate synthetase IMetabolism and bioenergetics · set 1 · hard

Chem/Phys 41

  1. Complementary launch anglesMotion, forces, and energy · set 4 · hard
  2. Minimum speed at the top of a loopMotion, forces, and energy · set 1 · hard
  3. Energy lost to friction on a rampMotion, forces, and energy · set 7 · hard
  4. Torque at an angleMotion, forces, and energy · set 6 · hard
  5. Recoil and conservation of momentumMotion, forces, and energy · set 5 · hard
  6. Is the collision elastic?Motion, forces, and energy · set 5 · hard
  7. Bernoulli's equation: pressure in a narrower pipeFluids and gases · set 3 · hard
  8. Compensating for a narrowed vesselFluids and gases · set 3 · hard
  9. Final temperature after mixing waterThermodynamics, kinetics, and equilibrium · set 4 · hard
  10. When real gases deviate from ideal behaviorFluids and gases · set 4 · hard
  11. Molar mass from gas densityFluids and gases · set 4 · hard
  12. Current through one branch of a combined circuitElectricity, magnetism, and electrochemistry · set 2 · hard
  13. Which parallel resistor dissipates more power?Electricity, magnetism, and electrochemistry · set 3 · hard
  14. The RC time constantElectricity, magnetism, and electrochemistry · set 1 · hard
  15. Radius of circular motion in a magnetic fieldElectricity, magnetism, and electrochemistry · set 6 · hard
  16. Where the electric field is zeroElectricity, magnetism, and electrochemistry · set 5 · hard
  17. Work along an equipotential surfaceElectricity, magnetism, and electrochemistry · set 5 · hard
  18. Converging lens: object inside the focal lengthLight and sound · set 3 · hard
  19. Concave mirror: finding the imageLight and sound · set 3 · hard
  20. Critical angle from glass to airLight and sound · set 3 · hard
  21. Doppler shift for a moving sourceLight and sound · set 5 · hard
  22. Half-life from a drop in activityAtoms and nuclear physics · set 3 · hard
  23. Identifying positron emissionAtoms and nuclear physics · set 3 · hard
  24. Mass–energy equivalenceAtoms and nuclear physics · set 3 · hard
  25. Choosing a buffer for pH 7.4Solutions, acids, and bases · set 2 · hard
  26. pH of a weak acid solutionSolutions, acids, and bases · set 1 · hard
  27. Solubility from K<sub>sp</sub> for a 1:2 saltSolutions, acids, and bases · set 2 · hard
  28. Standard cell potentialElectricity, magnetism, and electrochemistry · set 3 · hard
  29. ΔG° from cell potentialElectricity, magnetism, and electrochemistry · set 3 · hard
  30. Reaction enthalpy from bond enthalpiesThermodynamics, kinetics, and equilibrium · set 4 · hard
  31. Rate law from a mechanismThermodynamics, kinetics, and equilibrium · set 3 · hard
  32. Calculating Q to predict directionThermodynamics, kinetics, and equilibrium · set 2 · hard
  33. SN1 with a tertiary substrateBiomolecules and organic chemistry · set 1 · hard
  34. Counting stereoisomersBiomolecules and organic chemistry · set 1 · hard
  35. TLC: which compound travels farthest?Separations and purification · set 1 · hard
  36. Maximum speed on a flat curveMotion, forces, and energy · set 1 · hard
  37. Calculating osmotic pressureSolutions, acids, and bases · set 3 · hard
  38. Temperature at which a reaction becomes spontaneousThermodynamics, kinetics, and equilibrium · set 5 · hard
  39. Equilibrium constant from ΔG°Thermodynamics, kinetics, and equilibrium · set 2 · hard
  40. Mass of copper plated by electrolysisElectricity, magnetism, and electrochemistry · set 4 · hard
  41. Nernst potential for potassiumElectricity, magnetism, and electrochemistry · set 4 · hard

Psych/Soc 27

  1. Moderator vs. mediator vs. confounding variableResearch design · set 2 · hard
  2. Signal detection: shifting the response criterionSensation and perception · set 2 · hard
  3. Habituation vs. sensory adaptationSensation and perception · set 2 · hard
  4. Kamin's blocking effectLearning and conditioning · set 2 · hard
  5. Latent inhibitionLearning and conditioning · set 2 · hard
  6. Partial reinforcement extinction effectLearning and conditioning · set 4 · hard
  7. Interpreting an interaction effectResearch design · set 2 · hard
  8. What a p-value meansData and statistics · set 2 · hard
  9. Changing α: Type I vs. Type II errorsData and statistics · set 2 · hard
  10. Confidence intervals that include zeroData and statistics · set 2 · hard
  11. Regression to the meanResearch design · set 2 · hard
  12. Convergent and discriminant validityResearch design · set 1 · hard
  13. Post-decision dissonancePersonality, motivation, and disorders · set 1 · hard
  14. Self-perception theory and foot-in-the-doorPersonality, motivation, and disorders · set 1 · hard
  15. Kelley's covariation modelSocial thinking and prejudice · set 1 · hard
  16. Milgram's variations: what reduced obedience mostSocial processes · set 2 · hard
  17. Stress, cortisol, and immune functionEmotion and stress · set 2 · hard
  18. Selective REM deprivation and REM reboundCognition, memory, and sleep · set 7 · hard
  19. Narcolepsy and orexinCognition, memory, and sleep · set 7 · hard
  20. Split-brain patients and the left visual fieldCognition, memory, and sleep · set 5 · hard
  21. EEG vs. fMRI: temporal resolutionCognition, memory, and sleep · set 5 · hard
  22. Antipsychotics and movement side effectsPersonality, motivation, and disorders · set 6 · hard
  23. Weber: class, status, and powerSocial inequality · set 1 · hard
  24. Marx: false consciousnessSocial inequality · set 1 · hard
  25. Calculating relative riskData and statistics · set 1 · hard
  26. Positive predictive value and prevalenceData and statistics · set 1 · hard
  27. Calculating positive predictive valueData and statistics · set 1 · hard